https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52909 Wed 01 Nov 2023 08:47:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54341 Tue 20 Feb 2024 16:12:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43821 +ß7⁺ gut-homing T cells appear to be linked to the pathophysiology of both FD and IBS. Studies in the area are complicated by poor phenotyping of patients into subgroups and the subtle nature of the immune activity involved in FD and IBS. CONCLUSIONS: Alterations in proportions of gut-homing T lymphocytes in both FD and IBS indicate that a loss of mucosal homeostasis may drive the symptoms of FD and IBS. There is indirect evidence that Th17 responses may play a role in FGIDs, however the evidence for a Th2 immune phenotype in FD and IBS is limited. Although immune involvement is evident, large, well-characterised patient cohorts are required to elucidate the immune mechanisms driving the development of FGIDs.]]> Tue 04 Oct 2022 10:29:25 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46900 Thu 08 Dec 2022 08:09:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36099 Thu 06 Feb 2020 11:37:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54935 Fri 22 Mar 2024 14:31:53 AEDT ]]>